Letheen Broth w/Tween, Modified
Intended Use
Letheen Broth with Tween, Modified is specifically designed for the recovery of microorganisms from cosmetics, facilitating accurate microbiological testing.
Product Summary and Explanation
Originally described by Weber and Black in 1948, Letheen Broth with Tween, Modified stands out as a highly nutritional solid medium that effectively neutralizes quaternary ammonium compounds commonly found in sanitizers. This crucial attribute allows for the reliable assessment of germicidal activity, as proper total neutralization of disinfectants prevents misleading results such as false negatives (no growth).
The formulation integrates Lecithin and Polysorbate 80 (commonly known as Tween) into Tryptone Glucose Extract (TGE) Agar, enhancing its efficacy. This innovative blend promotes a balanced medium, optimizing the growth conditions for microorganisms while neutralizing the effects of disinfectants. The medium follows the guidelines outlined in the FDA Bacteriological Analytical Manual and is an advanced modification of the original Letheen Broth Base.
With the FDA recommending Letheen Broth with Tween, Modified for microbiological testing in cosmetics, this product is essential for laboratories focused on ensuring the safety and compliance of cosmetic formulations. Its unique composition and ability to neutralize residual disinfectants make it an invaluable tool for microbiologists and quality control professionals alike.