Tryptic Soy Broth Modified, w/Novobiocin (7694)
Intended Use
Tryptic Soy Broth, Modified with Novobiocin is specially formulated for the selective enrichment of enterohemorrhagic E. coli (EHEC) in food samples. This medium aids in isolating the E. coli O157:H7 strain, known for its potential to cause serious health issues.
Product Summary and Explanation
Among the four recognized classes of enterovirulent E. coli that can lead to gastroenteritis, E. coli O157:H7 is particularly notorious. This pathogenic strain produces potent toxins, inflicting severe damage to the intestinal lining. Infections can result in symptoms such as:
- Potential complications like Hemolytic Uremic Syndrome (HUS)
HUS can severely affect renal function and is more prevalent in vulnerable populations, including young children under five and the elderly, with 2-7% of infections leading to this syndrome.
The emergence of E. coli O157:H7 was first documented in 1982, linked to contaminated hamburgers. Additional sources include:
- Unpasteurized milk and juice
- Swimming in or ingesting contaminated water
This Tryptic Soy Broth, Modified with Novobiocin, is essential for enriching food samples suspected of containing low levels of EHEC, providing a reliable foundation for subsequent pathogen testing and enhancing food safety protocols.
