Lowenstein-Jensen Medium (7245)
| Manufacturer |
Catalog Number |
Specialties |
| Acumedia |
244420* |
Not Applicable |
Intended Use
Lowenstein-Jensen Medium is expertly formulated for the isolation and differentiation of Mycobacterium spp. when used in conjunction with fresh egg and glycerol.
Product Summary and Explanation
Addressing the urgent worldwide health crisis of mycobacterial infections, particularly tuberculosis, Lowenstein-Jensen Medium is essential for diagnostic microbiology. With tuberculosis claiming nearly three million lives annually and the rise of non-tuberculous mycobacterial infections, the need for effective isolation techniques has never been greater. This medium supports the growth of at least 25 species of mycobacteria linked to human disease, aiding in the identification of destructive granulomas that can lead to severe complications.
Key Advantages
Utilizing egg-based media, Lowenstein-Jensen Medium offers two significant benefits:
- It supports a broad spectrum of mycobacteria, enhancing the ability to isolate different species.
- The growth of mycobacteria on this medium facilitates niacin testing, a critical step in confirming certain Mycobacterium species.
Additionally, it’s important to note that liquefaction may occur if the medium is exposed to proteolytic organisms, an aspect to be mindful of during use.
Composition Changes
Lowenstein-Jensen Medium is an innovative modification of the original Lowenstein Medium, fine-tuned by Jensen. This adaptation includes an adjustment of citrate and phosphate levels and the removal of Congo red dye, while simultaneously increasing the concentration of malachite green. Commonly employed in clinical laboratories, this medium is indispensable for isolating acid-fast organisms from both sterile and non-sterile sources.
Specifications
- Type: Egg-based treatment medium
- Compatibility: Mycobacterium spp.
- Testing Utility: Niacin testing support
